Intensified and integrated biomanufacturing technologies
Scalable and high-productivity manufacture of advanced therapies
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Scalable seed train intensification and automation for adherent cell cultures with the scale-X™ bioreactor
Achievement of large-scale, cost-efficient enzymatic cell collection from structured fixed-bed bioreactors to facilitate and de-risk seed train generation
Learn moreReaching high capacity without large-scale bioreactors
Redefining the concepts of scale and flexibility
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A Rapid Fixed-Bed Proof-of-Concept Bioreactor
Static cell cultivation and production process transferred to the scale-X™ hydro bioreactor.
Learn moreIntegrated continuous biomass estimation in fixed-bed bioreactors
Novel approach allows for real-time measurement of cell density in fixed-bed bioreactors
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Leveraging small-scale parallel bioreactor systems for reliable and scalable processing design
Our Product Manager Clément Dumont explains how an innovative fixed-bed small-scale parallel system will revolutionize process design & optimization steps resulting in an increased production capacity & quality.
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What if you could produce most of your viral products with a single manufacturing platform?
Addressing biomanufacturing challenges through flexible platform design for both adherent & suspension cell lines
Learn moreInnovative fixed-bed bioreactors unify adherent and suspension processing
Decouple process from technology for gene therapy manufacture
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Suspension-based viral vector production in scale-X fixed-bed bioreactor
Shake flask process transferred in a scale-X hydro fixed-bed bioreactor for Adenovirus production with HEK293 cells adapted to suspension.
Learn moreScalable rubella production in scale-X™ bioreactor with MRC-5 cells
Process optimization and scale-up from static flask to scale-X bioreactor with 30 m² cell growth surface.
Learn moreReconciling adherence and suspension approaches for gene therapy manufacture
Intensified and automated dual platform for increased flexibility in viral vector manufacture
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Successful process transfer of vaccine candidates in scale-X™ hydro bioreactor
Direct process reproduction from multi-layer bioreactor and roller bottles for four vaccine antigens using three different cell lines (CEF, WI-38 and Vero cells)
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Capitalize on reliable operations & technologies: start-up & assistance services
Univercells Technologies provides reliable service solutions and quality support & maintenance to help you maintain performance and maximum safety of the equipment.
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scale-X™ hydro bioreactor for early process development
The scale-X hydro bioreactor is a small-scale, single-use, structured fixed-bed bioreactor enabling direct process transfer from existing processing technology for rapid proof of concept within a reduced footprint.
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Promising Vero cell growth in scale-X™ bioreactors
Case study comparing adherent Vero cell growth on microcarriers and intensified, fixed-bed scale-X bioreactors hydro (2.4 m²) and carbo (10-30 m²). Results demonstrate the scale-X bioreactors as a suitable alternative to traditional technologies.
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NevoLine™ Upstream platform: integrated and automated solution for intensified virus manufacturing
The NevoLine™ Upstream system is a high-performance and automated platform for commercial virus manufacturing. It integrates all process steps from inoculation to midstream processing to deliver a ready for downstream bulk.
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Intensified & automated biomanufacturing technologies for gene therapies production
The scale-X™ bioreactor range and the NevoLine™ platform: integrated and automated solutions for an intensified AAV and Lentiviral vectors manufacturing.
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The NevoLine™ platform concept – developed by Univercells
Poster illustrates the key features, benefits and applications of the NevoLine concept with the emphasis on the first implementation of this approach – The NevoLine platform for trivalent polio vaccine (sIPV).
DownloadHomogenous HEK293 cell growth in scale-X™ bioreactor
Proof of concept for scalable adherent cell growth and adenovirus production
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scale-X™ carbo bioreactor system for rapid process development
The scale-X™ carbo system is a bench-scale automated cell culture system for expression and concentration of viral drug substance, suited for rapid process development and cost-effective clinical production.
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NevoLine™ sIPV platform: proof of concept – developed by Univercells
The NevoLine sIPV platform was designed and developed by Univercells as part of a $12M Grand Challenges grant awarded by the Bill & Melinda Gates Foundation. This proof of concept was developed to deliver affordable inactivated polio vaccine (sIPV) in a low footprint.
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Disruptive micro-facility – developed by Univercells
Poster presents the NevoLine concept to deliver affordable vaccine doses based on sIPV polio vaccine case study.
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