Evolving biomanufacturing technology
The NevoLine™ Upstream platform is an innovative biomanufacturing technology that delivers cost-effective viral production. This new generation platform builds on the successful proof of concept NevoLine™ sIPV designed to deliver affordable inactivated polio vaccines.
The high-performance, intensified platform features a flexible design to accommodate viral vaccines, gene therapies, and oncolytic virus production. With the NevoLine™ Upstream platform, automated GMP clinical and commercial-scale upstream production is achieved within a 3 m² footprint.
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Redefining upstream virus production
The NevoLine™ Upstream platform accommodates all unit operations from inoculation to midstream processing within a compact module.
Single-use assemblies can be selected and combined to meet your process requirements.
Features
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An integrated solution designed for flexibility
Benefits
High Performance
Achieve rapid commercial-scale capacity with drastically reduced operational expenditures and footprint
Flexibility
Combine single-use assemblies for a multitude of process designs
Reliability
Integrate all unit steps in a compact design with automated operations for reproducible results
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Related Publications
NevoLine™ Upstream Platform: Integrated and Automated Solution for Intensified Virus Manufacturing
The NevoLine™ Upstream system is a high-performance and automated platform for commercial virus manufacturing. It integrates all process steps from inoculation to midstream processing to deliver a ready for downstream bulk.
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Redefining virus manufacturing with the fully automated and integrated NevoLine™ Upstream platform
Discover the integrated and automated NevoLine Upstream platform. Get insight on its design aligning flexibility and productivity with various process configurations according to your process needs. Get insights on case studies for vaccine and gene therapy production.
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Development of a scalable manufacturing platform for viral vectors
A case study on AAV and Adenovirus vectors presented at ASGCT 23rd Annual meeting 2020 by our Deputy CTO, Tania Pereira Chilima
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Integrated solutions
Delivering products & services tailored to your process needs
The flexible design of the NevoLine™ Upstream platform enables a multitude of viral processes and applications. Univercells Technologies experts are available to discuss how to leverage the platform to meet your process needs.
Rapid facility deployment
Building capacity for your viral production
The NevoLine™ Upstream platform can be implemented in stick-built, pod-based, or prefabricated modular facilities for a cost-effective, flexible solution rapidly implemented.
Interested in seeing the NevoLine™ Upstream platform in a modular facility?