NevoLine™ Upstream

Evolving biomanufacturing technology

The NevoLine™ Upstream platform is an innovative biomanufacturing technology that delivers cost-effective viral production. This new generation platform builds on the successful proof of concept NevoLine™ sIPV  designed to deliver affordable inactivated polio vaccines.

The high-performance, intensified platform features a flexible design to accommodate viral vaccines, gene therapies, and oncolytic virus production. With the NevoLine™ Upstream platform, automated GMP clinical and commercial-scale upstream production is achieved within a 3 m² footprint.

NevoLine Upstream platform intensified and automated viral production Univercells Technologies

Watch & Listen

Redefining upstream virus production

The NevoLine™ Upstream platform accommodates all unit operations from inoculation to midstream processing within a compact module.

Single-use assemblies can be selected and combined to meet your process requirements.


Click & Learn

An integrated solution designed for flexibility

NevoLine Upstream platform for intensified and automated virus production - Univercells Technologies
Compact, ergonomic hardware design
Automated process control
Integrated scale-X™ nitro single-use fixed-bed bioreactor
Single or multi-step clarification
Single-use in-line or sequential tangential flow filtration (TFF)
Main specifications & compliance


High Performance

Achieve rapid commercial-scale capacity with drastically reduced operational expenditures and footprint


Combine single-use assemblies for a multitude of process designs


Integrate all unit steps in a compact design with automated operations for reproducible results

NevoLine Benefits


Related Publications


Integrated solutions

Delivering products & services tailored to your process needs

The flexible design of the NevoLine™ Upstream platform enables a multitude of viral processes and applications. Univercells Technologies experts are available to discuss how to leverage the platform to meet your process needs.

Rapid facility deployment

Building capacity for your viral production

The NevoLine™ Upstream platform can be implemented in stick-built, pod-based, or prefabricated modular facilities for a cost-effective, flexible solution rapidly implemented.
Interested in seeing the NevoLine™ Upstream platform in a modular facility?

Interested in the
NevoLine™ Upstream?