Breaking down the barriers to gene therapy production
An increasing number of gene therapy treatments for previously unmet indications are entering the clinical trial pathway. However, the global availability and affordability of current and future gene therapy products is threatened by the challenges associates to their manufacture.
Producing viral vectors using conventional technologies presents several limitations including scalability constraints, high manufacturing cost of goods (COGs), as well as a low productivity and reproducibility. In order to overcome these hurdles, manufacturing technologies must be re-designed with the aim of easing scale-up and reducing COGs.
Integrated solutions for an enhanced & cost-effective viral vector biomanufacturing
scale-X™ single-use bioreactor
NevoLine™ biomanufacturing platform
- A range featuring at its core a novel single-use high-density bioreactor for an enhanced upstream processing
- A comprehensive portfolio scalable by design adequate for R&D, clinical and commercial scale production
- A technology combining the principles of process intensification, automation and chaining to reduce footprint, capital and operation costs
A novel technology offering increased benefits throughout the production steps
Seamless transitions through process development, clinical validation and commercial manufacture
Offering the highest throughput per cleanroom surface compared with currently available technologies
Significant ooperating costs savings across the different stages of the product lifecycle