Industrial-Scale Adherent Seed Train Intensification and Automation

Simplifying cell expansion and harvest at industrial scale using low-footprint scale-X™ carbo bioreactors

Efficient expansion of adherent mammalian cells remains a critical bottleneck in the production of viral vaccines and advanced therapy medicinal products (ATMPs). Traditional seed train workflows are labor-intensive, time-consuming, and difficult to scale.

This application note presents an optimized, automated approach using the scale-X™ platform and cell collect module to streamline seed train operations, reduce risks, and enable efficient scale-up to industrial bioreactors.

What you’ll learn

  • How to reduce seed train timelines to just 4 days without compromising yield or performance
  • How to achieve 96–99% cell viability with consistent single-cell recovery
  • How to cut harvest volumes by up to ~70% vs. conventional flatware, simplifying downstream operations

Get the full data and process insights to optimize your adherent cell expansion strategy and scale efficiently.

Download the application note

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