Suspension-based viral vector production in scale-X fixed-bed bioreactor
Shake flask process transferred in a scale-X hydro fixed-bed bioreactor for Adenovirus production with HEK293 cells adapted to suspension.
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Scalable rubella production in scale-X™ bioreactor with MRC-5 cells
Process optimization and scale-up from static flask to scale-X bioreactor with 30 m² cell growth surface.
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Successful process transfer of vaccine candidates in scale-X™ hydro bioreactor
Direct process reproduction from multi-layer bioreactor and roller bottles for four vaccine antigens using three different cell lines (CEF, WI-38 and Vero cells)
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Promising Vero cell growth in scale-X™ bioreactors
Case study comparing adherent Vero cell growth on microcarriers and intensified, fixed-bed scale-X bioreactors hydro (2.4 m²) and carbo (10-30 m²). Results demonstrate the scale-X bioreactors as a suitable alternative to traditional technologies.
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Proof of concept for scalable adherent cell growth and adenovirus production
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