Univercells Technologies delivers novel biomanufacturing platforms as a direct answer to the growing demand for viral vaccines and viral vectors. We leverage integration and continuous processing principles to significantly reduce the overall manufacturing footprint and deliver cost-effective and scalable manufacturing of high-quality therapies.
A unique fixed-bed technology for intensified processes
The scale-X™ bioreactor delivers intensified production of adherent and suspension cells as well as viral products. Its unique proprietary structured fixed-bed design consist of spiral-wound alternating sheets of non-woven PET fabric and spacer netting.
Scalability in the scale-X bioreactor range relies on the principle of constant linear velocity of fluids with surface area increase. This ensures that the residence time remains constant at any scale.
The principles of integration and continuous processing
Our novel fixed-bed bioreactors are integrated within automated and continuous platforms. This enables a reduction in operational volume, manual operations and overall costs while delivering increased throughput per cleanroom surface.
Integration of unit steps into a single continuous and automated platform offers an alternative to stand-alone unit operations and equipment. The drastic footprint and cost reductions have been demonstrated through the NevoLine™ sIPV proof-of-concept. The scale-X™ carbo system and the NevoLine™ Upstream platform feature an in-line TFF concentration step delivering a continuously concentrated harvest for simplified purification.
Scalability from discovery to commercial manufacturing
The scale-X fixed-bed bioreactors are at the core of our biomanufacturing platforms.
Our portfolio covers applications from small-scale R&D to large-scale GMP commercial manufacturing.
The scale-X hydro system was developed to support early development activities.
The mid-scale scale-X carbo system bridges the gap from development to clinical production. The NevoLine Upstream platform, featuring the large-scale scale-X nitro bioreactor, provides a solution for cost-effective large capacity production.
Discover our products
scale-X™ hydro system
Small-scale production for early-stage process development
scale-X™ carbo system
Low-footprint, intermediate-scale process development and GMP production
NevoLine™ Upstream platform
Integrated and automated commercial upstream manufacturing